Effects of Diet on Memory

Predicting the Effects of a High-Energy Diet on Fatty Liver and Hippocampal- Dependent Memory in Male Rats

Objective: In rodents, diets exceeding nutritional requirements (i.e., high-energy diets; HED) impair hippocampal-dependent memory. Our research suggests that the effects likely involve HED-induced increases in liver lipids. In this experiment, rats were provided with diet choices to test whether voluntary consumption of a HED impairs spatial memory, whether differences in initial weight gain predict memory… more »